| Bioactivity | [Phe2]-TRH is a thyrotropin releasing hormone analogue, equipping a conformational similarity with Leu5-enkephalin[1]. |
| Invitro | [Phe2]-TRH对 TRH 受体的亲和力低于 TRH 本身，并且在 [Phe2, azPro3]-TRH 类似物中用 azPro 替代 Pro 导致亲和力进一步损失约 200 倍[1]。 |
| Name | [Phe2]-TRH |
| CAS | 34783-35-2 |
| Shortening | Glp-FP-NH2 |
| Formula | C19H24N4O4 |
| Molar Mass | 372.42 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Eckle E, et al. Conformational properties of central nervous system active thyrotropin releasing hormone analogues: probing structure-activity relationships at the molecular level. J Med Chem. 1985 Jan;28(1):125-37. [2]. Zhang WJ, et al. Impact of azaproline on amide cis-trans isomerism: conformational analyses and NMR studies of model peptides including TRH analogues. J Am Chem Soc. 2003 Feb 5;125(5):1221-35. |